Smith, who didn't practice all week, is listed as "doubtful." This means there is a 25 percent change he could play.
Smith suffered a serious head injury in San Francisco last Sunday when he was leveled by LB Patrick Willis on a pass over the middle. The injury took place in the fourth quarter.
But for some reason he's not listed as "out," so perhaps Mangini is holding out hope that the wide receiver will still be able to play against Buffalo on Sunday.